Betting San Francisco 49ers vs. Arizona Cardinals

49ers vs. Cardinals 2019
  • The 49ers remain undefeated through the nine weeks of NFL regular season. San Francisco opened as a 7-point home favorite, but the line has ticked up to -8.
  • The Cardinals were handed a 31-9 loss by the New Orleans Saints last week. Arizona is no 3-4-1 SU and 5-3 ATS.

Betting San Francisco 49ers vs. Arizona Cardinals

The 49ers roll into Arizona as double-digit chalk in this Halloween matchup on Thursday Night Football. Can the 49ers cover, or will the Cardinals keep it close? Keep reading for the free pick.

  • When: October 31, 2019, 8:20 PM ET
  • Where: State Farm Stadium
  • NFL latest line: 49ers -10
  • Over/Under: 43
  • Moneyline: 49ers -465 vs. Cardinals +360

How’s the weather?

  • Sunny
  • 26°C/79°F
  • Humidity: 18%
  • Precipitation %  0%
  • Cloud Cover: 8%
  • Wind: 6 mph NNE
  • Stadium Type: Retractable

Should You Bet on the 49ers?  

The 49ers put up points on the scoreboard blazingly fast, scoring first in seven of their eight games played. San Francisco is undefeated and playing great football on both sides of the ball.

The 49ers have arguably the best first-quarter offenses in the league, scoring an average of 7.4 points in the first 15 minutes of the game. However, San Francisco is playing on the road and on a short-week scenario, which means covering the 10 points might be stretching things.

The sharp money pushed the early 8-point line to what it is right now, and if the public follows suit, then it might go up half a point, which is something to consider if you’re betting ATS.

Last 3 Head-to-Head Record

  • Score: 14.33
  • Rush Yds.: 105.67
  • Pass Attempts: 44.33
  • Completion %: 54.14
  • Passing Yds. 242.00
  • Total Yds. 347.67
  • Turnovers: 2.33

Should You Bet on the Cardinals?  

The Cardinals saw their three-game win streak snapped like a twig by the New Orleans Saints last Sunday. The Saints defense bogged down Arizona’s offense and kept them to just 40 rushing yards and 273 total yards.

The Cardinals are also missing some key offensive players, which means they could be in even hotter waters in facing San Francisco’s stout defense. The 49ers are the 11th-ranked run defense, so don’t expect Arizona to be gaining much ground in the game.

Going to the air attack also might not work out against the 49ers, whose defense has allowed a league-low 128.7 pass yards per game this season.

Last 3 Head-to-Head Record

  • Score: 22.00
  • Rush Yds.: 103.67
  • Pass Attempts: 31.67
  • Completion %: 50.53
  • Passing Yds. 199.33
  • Total Yds. 303
  • Turnovers: 1.33

Betting Trends

  • San Francisco is 5-2 ATS in their last seven games.
  • The total has gone UNDER in 4 of San Francisco's last five games.
  • San Francisco is 7-0 SU in their last seven games.
  • Arizona is 6-3 ATS in their last nine games.
  • Arizona is 4-11-1 SU in their last 16 games.
  • The total has gone UNDER in 4 of Arizona's last five games against San Francisco.

Insider Prediction: The 49ers will win, but covering at 10 points is stretching it. Arizona will have a difficult time to put points up on the scoreboard, but that doesn’t mean they won’t keep things close.

Pick: Cardinals +10